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Target
Regulator of G-protein signaling 8
Ligand
BDBM47789
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47789
Synonyms:
1-(2-chloranyl-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitrophenyl)-3-methylpiperazine;hydrochloride | MLS000722903 | SMR000304898 | cid_2771392
Type:
Small organic molecule
Emp. Form.:
C11H14ClN3O2
Mol. Mass.:
255.701
SMILES:
CC1CN(CCN1)c1ccc(cc1Cl)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: