Target
Regulator of G-protein signaling 8
Ligand
BDBM47796
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47796
Synonyms:
(E)-1-(3,5-dimethyl-1-piperidinyl)-3-(5-nitro-2-thiophenyl)-2-propen-1-one | (E)-1-(3,5-dimethylpiperidin-1-yl)-3-(5-nitrothiophen-2-yl)prop-2-en-1-one | (E)-1-(3,5-dimethylpiperidino)-3-(5-nitro-2-thienyl)prop-2-en-1-one | MLS000703523 | SMR000322939 | cid_6012169
Type:
Small organic molecule
Emp. Form.:
C14H18N2O3S
Mol. Mass.:
294.369
SMILES:
CC1CC(C)CN(C1)C(=O)\C=C\c1ccc(s1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: