Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 8
Ligand
BDBM47809
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47809
Synonyms:
(2S)-2-[[5-(benzylcarbamoyl)-1H-imidazole-4-carbonyl]amino]propionic acid tert-butyl ester | (2S)-2-[[oxo-[5-[oxo-[(phenylmethyl)amino]methyl]-1H-imidazol-4-yl]methyl]amino]propanoic acid tert-butyl ester | ILP-II-19 | MLS000834697 | SMR000394106 | cid_16196485 | tert-butyl (2S)-2-[[5-(benzylcarbamoyl)-1H-imidazole-4-carbonyl]amino]propanoate | tert-butyl (2S)-2-[[5-[(phenylmethyl)carbamoyl]-1H-imidazol-4-yl]carbonylamino]propanoate
Type:
Small organic molecule
Emp. Form.:
C19H24N4O4
Mol. Mass.:
372.4183
SMILES:
C[C@H](NC(=O)c1nc[nH]c1C(=O)NCc1ccccc1)C(=O)OC(C)(C)C
Structure:
Search PDB for entries with ligand similarity: