Target
Regulator of G-protein signaling 8
Ligand
BDBM47830
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47830
Synonyms:
4-cyclopropyl-6-(methylthio)-1,3,5-triazin-2-amine | 4-cyclopropyl-6-methylsulfanyl-1,3,5-triazin-2-amine | MLS000861275 | SMR000460059 | [4-cyclopropyl-6-(methylthio)-s-triazin-2-yl]amine | cid_602660
Type:
Small organic molecule
Emp. Form.:
C7H10N4S
Mol. Mass.:
182.246
SMILES:
CSc1nc(N)nc(n1)C1CC1
Structure:
Search PDB for entries with ligand similarity: