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Target
Regulator of G-protein signaling 8
Ligand
BDBM47833
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47833
Synonyms:
2-[2-(hydroxymethyl)phenyl]sulfanyl-N-methyl-benzamide | 2-[2-(hydroxymethyl)phenyl]sulfanyl-N-methylbenzamide | 2-[[2-(hydroxymethyl)phenyl]thio]-N-methylbenzamide | MLS000861000 | N-methyl-2-[(2-methylolphenyl)thio]benzamide | N1-methyl-2-{[2-(hydroxymethyl)phenyl]thio}benzamide | SMR000459784 | cid_2824943
Type:
Small organic molecule
Emp. Form.:
C15H15NO2S
Mol. Mass.:
273.35
SMILES:
CNC(=O)c1ccccc1Sc1ccccc1CO
Structure:
Search PDB for entries with ligand similarity: