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Target
Regulator of G-protein signaling 7
Ligand
BDBM47702
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47702
Synonyms:
MLS000089261 | N-(5-methyl-2-pyridin-2-yl-pyrazol-3-yl)cyclobutanecarboxamide | N-(5-methyl-2-pyridin-2-ylpyrazol-3-yl)cyclobutanecarboxamide | N-[5-methyl-2-(2-pyridinyl)-3-pyrazolyl]cyclobutanecarboxamide | N-[5-methyl-2-(2-pyridyl)pyrazol-3-yl]cyclobutanecarboxamide | SMR000062562 | cid_2997575
Type:
Small organic molecule
Emp. Form.:
C14H16N4O
Mol. Mass.:
256.303
SMILES:
Cc1cc(NC(=O)C2CCC2)n(n1)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: