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Target
Regulator of G-protein signaling 7
Ligand
BDBM47767
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47767
Synonyms:
3-(phenoxymethyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-3-(phenoxymethyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-5-(phenoxymethyl)-4H-1,2,4-triazole-3-thiol | MLS000676944 | SMR000271129 | cid_702854
Type:
Small organic molecule
Emp. Form.:
C16H15N3OS
Mol. Mass.:
297.375
SMILES:
S=c1[nH]nc(COc2ccccc2)n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: