Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 7
Ligand
BDBM47771
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47771
Synonyms:
2-[(2-methylsulfanylphenyl)carbamoyl]bicyclo[2.2.1]heptane-3-carboxylic acid | 2-[[2-(methylthio)anilino]-oxomethyl]-3-bicyclo[2.2.1]heptanecarboxylic acid | 3-({[2-(methylthio)phenyl]amino}carbonyl)bicyclo[2.2.1]heptane-2-carboxylic acid | 3-[[2-(methylthio)phenyl]carbamoyl]norbornane-2-carboxylic acid | MLS000663283 | SMR000301317 | cid_4671471
Type:
Small organic molecule
Emp. Form.:
C16H19NO3S
Mol. Mass.:
305.392
SMILES:
[H]C12CCC([H])(C1)C(C2C(O)=O)C(=O)Nc1ccccc1SC |TLB:12:7:6:3.2,THB:9:8:6:3.2|
Structure:
Search PDB for entries with ligand similarity: