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Target
Regulator of G-protein signaling 7
Ligand
BDBM47779
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47779
Synonyms:
2-furanyl-[4-[3-(4-morpholinyl)-4-nitrophenyl]-1-piperazinyl]methanone | 2-furyl-[4-(3-morpholino-4-nitro-phenyl)piperazino]methanone | MLS000711509 | SMR000281276 | cid_2894898 | furan-2-yl-[4-(3-morpholin-4-yl-4-nitro-phenyl)piperazin-1-yl]methanone | furan-2-yl-[4-(3-morpholin-4-yl-4-nitrophenyl)piperazin-1-yl]methanone
Type:
Small organic molecule
Emp. Form.:
C19H22N4O5
Mol. Mass.:
386.4018
SMILES:
[O-][N+](=O)c1ccc(cc1N1CCOCC1)N1CCN(CC1)C(=O)c1ccco1
Structure:
Search PDB for entries with ligand similarity: