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Target
Regulator of G-protein signaling 7
Ligand
BDBM47807
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47807
Synonyms:
(2S)-2-[[5-[[(1R)-1-phenylethyl]carbamoyl]-1H-imidazole-4-carbonyl]amino]propionic acid tert-butyl ester | (2S)-2-[[oxo-[5-[oxo-[[(1R)-1-phenylethyl]amino]methyl]-1H-imidazol-4-yl]methyl]amino]propanoic acid tert-butyl ester | MLS000834661 | SMR000391241 | cid_16196412 | tert-butyl (2S)-2-[[5-[[(1R)-1-phenylethyl]carbamoyl]-1H-imidazol-4-yl]carbonylamino]propanoate | tert-butyl (2S)-2-[[5-[[(1R)-1-phenylethyl]carbamoyl]-1H-imidazole-4-carbonyl]amino]propanoate
Type:
Small organic molecule
Emp. Form.:
C20H26N4O4
Mol. Mass.:
386.4448
SMILES:
C[C@H](NC(=O)c1nc[nH]c1C(=O)N[C@H](C)c1ccccc1)C(=O)OC(C)(C)C
Structure:
Search PDB for entries with ligand similarity: