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Target
Regulator of G-protein signaling 7
Ligand
BDBM47832
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47832
Synonyms:
1-N-(1-benzothiophen-3-yl)piperidine-1,4-dicarboxamide | MLS000858903 | N-(benzothiophen-3-yl)piperidine-1,4-dicarboxamide | N1-(1-benzothiophen-3-yl)piperidine-1,4-dicarboxamide | N~1~-(1-benzothiophen-3-yl)tetrahydro-1,4(2H)-pyridinedicarboxamide | SMR000458982 | cid_2816288
Type:
Small organic molecule
Emp. Form.:
C15H17N3O2S
Mol. Mass.:
303.379
SMILES:
NC(=O)C1CCN(CC1)C(=O)Nc1csc2ccccc12
Structure:
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