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Target
Regulator of G-protein signaling 19
Ligand
BDBM47732
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
1000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
  
Inhibitor
Name:
BDBM47732
Synonyms:
2,6,7-trihydroxy-9-o-phenetyl-fluorone | 9-(2-ethoxyphenyl)-2,6,7-trihydroxy-3-xanthenone | 9-(2-ethoxyphenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 9-(2-ethoxyphenyl)-2,6,7-trihydroxyxanthen-3-one | 9-(2-ethoxyphenyl)-2,6,7-tris(oxidanyl)xanthen-3-one | MLS000578271 | SMR000197680 | cid_2931388
Type:
Small organic molecule
Emp. Form.:
C21H16O6
Mol. Mass.:
364.3481
SMILES:
CCOc1ccccc1-c1c2cc(O)c(O)cc2oc2cc(=O)c(O)cc12 |(13.35,3.58,;13.35,2.04,;12.01,1.27,;10.68,2.04,;10.68,3.58,;9.35,4.35,;8.01,3.58,;8.01,2.04,;9.35,1.27,;9.35,-.27,;10.68,-1.04,;12.06,-.22,;13.45,-1.01,;14.78,-.24,;13.45,-2.62,;14.78,-3.39,;12.06,-3.41,;10.68,-2.58,;9.35,-3.35,;8.01,-2.58,;6.63,-3.41,;5.24,-2.62,;3.91,-3.39,;5.24,-1.01,;3.91,-.24,;6.63,-.22,;8.01,-1.04,)|
Structure:
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