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Target
Regulator of G-protein signaling 19
Ligand
BDBM47751
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
  
Inhibitor
Name:
BDBM47751
Synonyms:
4,5-dimethyl-2-[[2-(3-tosylpropanoyloxy)acetyl]amino]thiophene-3-carboxylic acid methyl ester | 4,5-dimethyl-2-[[2-[3-(4-methylphenyl)sulfonyl-1-oxopropoxy]-1-oxoethyl]amino]-3-thiophenecarboxylic acid methyl ester | MLS000335716 | SMR000253470 | cid_2115448 | methyl 4,5-dimethyl-2-[2-[3-(4-methylphenyl)sulfonylpropanoyloxy]ethanoylamino]thiophene-3-carboxylate | methyl 4,5-dimethyl-2-[[2-[3-(4-methylphenyl)sulfonylpropanoyloxy]acetyl]amino]thiophene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C20H23NO7S2
Mol. Mass.:
453.529
SMILES:
COC(=O)c1c(C)c(C)sc1NC(=O)COC(=O)CCS(=O)(=O)c1ccc(C)cc1
Structure:
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