Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 19
Ligand
BDBM34849
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
460±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
  
Inhibitor
Name:
BDBM34849
Synonyms:
6-fluoranyl-2-(2-methylphenyl)-1,2-benzothiazol-3-one | 6-fluoro-2-(2-methylphenyl)-1,2-benzisothiazol-3(2H)-one | 6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one | 6-fluoro-2-(o-tolyl)-1,2-benzothiazol-3-one | MLS000729299 | SMR000307577 | cid_1510379
Type:
Small organic molecule
Emp. Form.:
C14H10FNOS
Mol. Mass.:
259.299
SMILES:
Cc1ccccc1-n1sc2cc(F)ccc2c1=O
Structure:
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