Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 19
Ligand
BDBM47789
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
  
Inhibitor
Name:
BDBM47789
Synonyms:
1-(2-chloranyl-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitrophenyl)-3-methylpiperazine;hydrochloride | MLS000722903 | SMR000304898 | cid_2771392
Type:
Small organic molecule
Emp. Form.:
C11H14ClN3O2
Mol. Mass.:
255.701
SMILES:
CC1CN(CCN1)c1ccc(cc1Cl)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: