Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 19
Ligand
BDBM47799
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
>30000±n/a nM
Citation
PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID]
More Info.:
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
Inhibitor
Name:
BDBM47799
Synonyms:
2-(benzenesulfonyl)-N-[4-(2-pyrimidinylsulfamoyl)phenyl]acetamide | 2-(benzenesulfonyl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide | 2-(phenylsulfonyl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]ethanamide | 2-besyl-N-[4-(2-pyrimidylsulfamoyl)phenyl]acetamide | MLS000716743 | SMR000278260 | cid_4428810
Type:
Small organic molecule
Emp. Form.:
C18H16N4O5S2
Mol. Mass.:
432.473
SMILES:
O=C(CS(=O)(=O)c1ccccc1)Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1