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Target
Regulator of G-protein signaling 19
Ligand
BDBM47814
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 19
Synonyms:
G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24631.38
Organism:
Homo sapiens (Human)
Description:
gi_86990435
Residue:
217
Sequence:
MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDAQLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
  
Inhibitor
Name:
BDBM47814
Synonyms:
MLS000762557 | N-(4-acetyl-2'-keto-5',7'-dimethyl-1'-propyl-spiro[1,3,4-thiadiazole-5,3'-indoline]-2-yl)acetamide | N-(4-acetyl-5',7'-dimethyl-2'-oxo-1'-propyl-2-spiro[1,3,4-thiadiazole-5,3'-indole]yl)acetamide | N-(4-acetyl-5',7'-dimethyl-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide | N-(4-ethanoyl-5',7'-dimethyl-2'-oxidanylidene-1'-propyl-spiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)ethanamide | SMR000438088 | cid_4270177
Type:
Small organic molecule
Emp. Form.:
C18H22N4O3S
Mol. Mass.:
374.457
SMILES:
CCCN1C(=O)C2(SC(NC(C)=O)=NN2C(C)=O)c2cc(C)cc(C)c12 |c:12|
Structure:
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