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Target
Regulator of G-protein signaling 16
Ligand
BDBM47746
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47746
Synonyms:
MLS000374437 | N-(1-iminoisoindolin-2-yl)-3-morpholinosulfonyl-benzamide | N-(3-azanylidene-1H-isoindol-2-yl)-3-morpholin-4-ylsulfonyl-benzamide | N-(3-imino-1H-isoindol-2-yl)-3-(4-morpholinylsulfonyl)benzamide | N-(3-imino-1H-isoindol-2-yl)-3-morpholin-4-ylsulfonylbenzamide | SMR000242353 | cid_5183675
Type:
Small organic molecule
Emp. Form.:
C19H20N4O4S
Mol. Mass.:
400.451
SMILES:
N=C1N(Cc2ccccc12)NC(=O)c1cccc(c1)S(=O)(=O)N1CCOCC1
Structure:
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