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Target
Regulator of G-protein signaling 16
Ligand
BDBM47751
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47751
Synonyms:
4,5-dimethyl-2-[[2-(3-tosylpropanoyloxy)acetyl]amino]thiophene-3-carboxylic acid methyl ester | 4,5-dimethyl-2-[[2-[3-(4-methylphenyl)sulfonyl-1-oxopropoxy]-1-oxoethyl]amino]-3-thiophenecarboxylic acid methyl ester | MLS000335716 | SMR000253470 | cid_2115448 | methyl 4,5-dimethyl-2-[2-[3-(4-methylphenyl)sulfonylpropanoyloxy]ethanoylamino]thiophene-3-carboxylate | methyl 4,5-dimethyl-2-[[2-[3-(4-methylphenyl)sulfonylpropanoyloxy]acetyl]amino]thiophene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C20H23NO7S2
Mol. Mass.:
453.529
SMILES:
COC(=O)c1c(C)c(C)sc1NC(=O)COC(=O)CCS(=O)(=O)c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: