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Target
Regulator of G-protein signaling 16
Ligand
BDBM47825
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47825
Synonyms:
MLS000780308 | N-Acetyl-N'-(5-nitro-benzooxazol-2-yl)-guanidine | N-[(E)-N'-(5-nitro-1,3-benzoxazol-2-yl)amidino]acetamide | N-[(E)-N'-(5-nitro-1,3-benzoxazol-2-yl)carbamimidoyl]acetamide | N-[(E)-N'-(5-nitro-1,3-benzoxazol-2-yl)carbamimidoyl]ethanamide | N-[(E)-amino-[(5-nitro-1,3-benzoxazol-2-yl)imino]methyl]acetamide | SMR000420491 | cid_16411063
Type:
Small organic molecule
Emp. Form.:
C10H9N5O4
Mol. Mass.:
263.2096
SMILES:
CC(=O)[NH+]=C(N)[N-]c1nc2cc(ccc2o1)[N+]([O-])=O |w:3.2|
Structure:
Search PDB for entries with ligand similarity: