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Target
3C-like protease
Ligand
BDBM47843
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
4633±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47843
Synonyms:
1-(5-phenyl-2-pyrrolidin-1-yl-1H-pyrrol-3-yl)ethanone | 1-(5-phenyl-2-pyrrolidino-1H-pyrrol-3-yl)ethanone | 1-[5-phenyl-2-(1-pyrrolidinyl)-1H-pyrrol-3-yl]ethanone | MLS000061991 | SMR000070852 | cid_880528
Type:
Small organic molecule
Emp. Form.:
C16H18N2O
Mol. Mass.:
254.3269
SMILES:
CC(=O)c1cc([nH]c1N1CCCC1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: