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Target
3C-like protease
Ligand
BDBM47865
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
16057±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47865
Synonyms:
(2-oxidanylidene-2-phenothiazin-10-yl-ethyl) pyridine-3-carboxylate | (2-oxo-2-phenothiazin-10-ylethyl) pyridine-3-carboxylate | 3-pyridinecarboxylic acid [2-oxo-2-(10-phenothiazinyl)ethyl] ester | MLS001011265 | SMR000353241 | cid_2352096 | nicotinic acid (2-keto-2-phenothiazin-10-yl-ethyl) ester
Type:
Small organic molecule
Emp. Form.:
C20H14N2O3S
Mol. Mass.:
362.402
SMILES:
O=C(COC(=O)c1cccnc1)N1c2ccccc2Sc2ccccc12
Structure:
Search PDB for entries with ligand similarity: