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Target
3C-like protease
Ligand
BDBM47869
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
13369±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47869
Synonyms:
MLS000771302 | N-(4-bromanyl-3-methyl-phenyl)-2-(6-methylsulfonylbenzotriazol-1-yl)oxy-ethanamide | N-(4-bromo-3-methyl-phenyl)-2-(6-mesylbenzotriazol-1-yl)oxy-acetamide | N-(4-bromo-3-methylphenyl)-2-(6-methylsulfonylbenzotriazol-1-yl)oxyacetamide | N-(4-bromo-3-methylphenyl)-2-[(6-methylsulfonyl-1-benzotriazolyl)oxy]acetamide | SMR000344410 | cid_2515806
Type:
Small organic molecule
Emp. Form.:
C16H15BrN4O4S
Mol. Mass.:
439.284
SMILES:
Cc1cc(NC(=O)COn2nnc3ccc(cc23)S(C)(=O)=O)ccc1Br
Structure:
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