Target
3C-like protease
Ligand
BDBM47879
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
24150±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47879
Synonyms:
(E)-3-(2-chlorophenyl)-N-(3-pyridinyl)-2-propenamide | (E)-3-(2-chlorophenyl)-N-(3-pyridyl)acrylamide | (E)-3-(2-chlorophenyl)-N-pyridin-3-yl-prop-2-enamide | (E)-3-(2-chlorophenyl)-N-pyridin-3-ylprop-2-enamide | MLS001185439 | SMR000503026 | cid_676085
Type:
Small organic molecule
Emp. Form.:
C14H11ClN2O
Mol. Mass.:
258.703
SMILES:
Clc1ccccc1\C=C\C(=O)Nc1cccnc1
Structure:
Search PDB for entries with ligand similarity: