Target
3C-like protease
Ligand
BDBM47895
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
9097±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47895
Synonyms:
MLS001215963 | N-[5-fluoranyl-1-(2-morpholin-4-ylethyl)-2-oxidanylidene-3H-indol-3-yl]ethanamide;hydrochloride | N-[5-fluoro-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydrochloride | N-[5-fluoro-1-[2-(4-morpholinyl)ethyl]-2-oxo-3H-indol-3-yl]acetamide;hydrochloride | N-[5-fluoro-2-keto-1-(2-morpholinoethyl)indolin-3-yl]acetamide;hydrochloride | SMR000544632 | cid_24761173
Type:
Small organic molecule
Emp. Form.:
C16H20FN3O3
Mol. Mass.:
321.3467
SMILES:
CC(=O)NC1C(=O)N(CCN2CCOCC2)c2ccc(F)cc12
Structure:
Search PDB for entries with ligand similarity: