Target
3C-like protease
Ligand
BDBM47905
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
5195±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47905
Synonyms:
2-chloranyl-1-[3-(furan-2-yl)-5-(5-methylfuran-2-yl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(2-furanyl)-5-(5-methyl-2-furanyl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[3-(furan-2-yl)-5-(5-methylfuran-2-yl)-3,4-dihydropyrazol-2-yl]ethanone | 2-chloro-1-[5-(2-furyl)-3-(5-methyl-2-furyl)-2-pyrazolin-1-yl]ethanone | MLS001179882 | SMR000595582 | cid_4961646
Type:
Small organic molecule
Emp. Form.:
C14H13ClN2O3
Mol. Mass.:
292.718
SMILES:
Cc1ccc(o1)C1=NN(C(C1)c1ccco1)C(=O)CCl |t:7|
Structure:
Search PDB for entries with ligand similarity: