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Target
3C-like protease
Ligand
BDBM47913
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
7068±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47913
Synonyms:
MLS001030320 | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-(2-pyridinylthio)acetamide | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanyl-ethanamide | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanylacetamide | N-(4-nitrofurazan-3-yl)-2-(2-pyridylthio)acetamide | SMR000635635 | cid_4917203
Type:
Small organic molecule
Emp. Form.:
C9H7N5O4S
Mol. Mass.:
281.248
SMILES:
[O-][N+](=O)c1nonc1NC(=O)CSc1ccccn1
Structure:
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