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Target
3C-like protease
Ligand
BDBM47926
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
4877±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47926
Synonyms:
2-(3-amino-3-oxopropyl)-3-(4-chlorobenzoyl)-2H-indazole 1-oxide | 3-[3-(4-chlorobenzoyl)-1-oxido-indazol-1-ium-2-yl]propionamide | 3-[3-(4-chlorobenzoyl)-1-oxidoindazol-1-ium-2-yl]propanamide | 3-[3-(4-chlorophenyl)carbonyl-1-oxidanidyl-indazol-1-ium-2-yl]propanamide | 3-[3-[(4-chlorophenyl)-oxomethyl]-1-oxido-2-indazol-1-iumyl]propanamide | MLS001097193 | SMR000718358 | cid_24817257
Type:
Small organic molecule
Emp. Form.:
C17H14ClN3O3
Mol. Mass.:
343.764
SMILES:
NC(=O)CCn1c(C(=O)c2ccc(Cl)cc2)c2ccccc2[n+]1[O-]
Structure:
Search PDB for entries with ligand similarity: