Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46252
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies
IC50
4840±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46252
Synonyms:
(4E)-2-methoxy-4-[[(phenylmethyl)amino]-sulfanyl-methylidene]cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-mercapto-methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[(benzylamino)-sulfanylmethylidene]-2-methoxycyclohexa-2,5-dien-1-one | (4E)-4-[mercapto-[(phenylmethyl)amino]methylidene]-2-methoxy-1-cyclohexa-2,5-dienone | MLS-0412121.0001 | cid_20110352
Type:
Small organic molecule
Emp. Form.:
C15H15NO2S
Mol. Mass.:
273.35
SMILES:
COc1cc(ccc1O)C(=S)NCc1ccccc1
Structure:
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