Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46262
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46262
Synonyms:
4-chloranyl-3-sulfamoyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide | 4-chloro-3-sulfamoyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide | 4-chloro-3-sulfamoyl-N-tetralin-1-yl-benzamide | MLS-0412137.0001 | cid_25048313
Type:
Small organic molecule
Emp. Form.:
C17H17ClN2O3S
Mol. Mass.:
364.846
SMILES:
NS(=O)(=O)c1cc(ccc1Cl)C(=O)NC1CCCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: