Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM46209
Substrate
n/a
Meas. Tech.
SAR VHR1 absorbance Assay for In Vitro dose response studies.
IC50
12500±n/a nM
Citation
 PubChem, PC SAR VHR1 absorbance Assay for In Vitro dose response studies. PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46209
Synonyms:
1-cyclopropyl-3-(4-sulfamoylphenyl)thiourea | MLS-0065250.0001 | cid_891589
Type:
Small organic molecule
Emp. Form.:
C10H13N3O2S2
Mol. Mass.:
271.359
SMILES:
NS(=O)(=O)c1ccc(NC(=S)NC2CC2)cc1
Structure:
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