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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48115
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
50000±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48115
Synonyms:
3-(2-Chloro-benzyl)-7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-carboxylic acid (thiophen-2-ylmethyl)-amide | 3-(2-chlorobenzyl)-7-keto-N-(2-thenyl)-2H-triazolo[4,5-d]pyrimidine-5-carboxamide | 3-[(2-chlorophenyl)methyl]-7-oxidanylidene-N-(thiophen-2-ylmethyl)-2H-[1,2,3]triazolo[4,5-d]pyrimidine-5-carboxamide | 3-[(2-chlorophenyl)methyl]-7-oxo-N-(thiophen-2-ylmethyl)-2H-triazolo[4,5-d]pyrimidine-5-carboxamide | MLS000074773 | SMR000007830 | cid_655750
Type:
Small organic molecule
Emp. Form.:
C17H13ClN6O2S
Mol. Mass.:
400.842
SMILES:
Clc1ccccc1Cn1nnc2c1nc([nH]c2=O)C(=O)NCc1cccs1
Structure:
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