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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48117
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
5820±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48117
Synonyms:
3-methyl-6-[(4-methylphenyl)sulfanylmethyl]imidazo[2,1-b][1,3]thiazole;hydrobromide | 3-methyl-6-[(p-tolylthio)methyl]imidazo[2,1-b]thiazole;hydrobromide | 3-methyl-6-[[(4-methylphenyl)thio]methyl]imidazo[2,1-b]thiazole;hydrobromide | MLS000068785 | SMR000040015 | cid_6603455
Type:
Small organic molecule
Emp. Form.:
C14H14N2S2
Mol. Mass.:
274.404
SMILES:
Cc1csc2nc(CSc3ccc(C)cc3)cn12
Structure:
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