Reaction Details Report a problem with these data
Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48142
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
12700±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48142
Synonyms:
5-propyl-N-(1,3-thiazol-2-yl)thiophene-3-carboxamide | 5-propyl-N-(2-thiazolyl)-3-thiophenecarboxamide | 5-propyl-N-1,3-thiazol-2-yl-3-thiophenecarboxamide | 5-propyl-N-thiazol-2-yl-thiophene-3-carboxamide | MLS000099818 | SMR000080806 | cid_1247663
Type:
Small organic molecule
Emp. Form.:
C11H12N2OS2
Mol. Mass.:
252.356
SMILES:
CCCc1cc(cs1)C(=O)Nc1nccs1
Structure:
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