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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48224
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
2880±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48224
Synonyms:
2-(1-Methyl-5-phenyl-1H-imidazol-2-ylsulfanyl)-1-piperidin-1-yl-ethanone | 2-(1-methyl-5-phenyl-imidazol-2-yl)sulfanyl-1-piperidin-1-yl-ethanone | 2-(1-methyl-5-phenylimidazol-2-yl)sulfanyl-1-piperidin-1-ylethanone | 2-[(1-methyl-5-phenyl-2-imidazolyl)thio]-1-(1-piperidinyl)ethanone | 2-[(1-methyl-5-phenyl-imidazol-2-yl)thio]-1-piperidino-ethanone | MLS000527404 | SMR000117878 | cid_864219
Type:
Small organic molecule
Emp. Form.:
C17H21N3OS
Mol. Mass.:
315.433
SMILES:
Cn1c(SCC(=O)N2CCCCC2)ncc1-c1ccccc1
Structure:
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