Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48281
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
3040±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48281
Synonyms:
(2-fluorophenyl)-[5-[1-(2-methoxyethyl)-2,5-dimethyl-pyrrol-3-yl]-6H-1,3,4-thiadiazin-2-yl]amine | MLS000564266 | N-(2-fluorophenyl)-5-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-6H-1,3,4-thiadiazin-2-amine | N-(2-fluorophenyl)-5-[1-(2-methoxyethyl)-2,5-dimethyl-pyrrol-3-yl]-6H-1,3,4-thiadiazin-2-amine | N-(2-fluorophenyl)-5-[1-(2-methoxyethyl)-2,5-dimethylpyrrol-3-yl]-6H-1,3,4-thiadiazin-2-amine | SMR000151762 | cid_3606829
Type:
Small organic molecule
Emp. Form.:
C18H21FN4OS
Mol. Mass.:
360.449
SMILES:
COCCn1c(C)cc(c1C)C1=NN=C(Nc2ccccc2F)SC1 |t:12,14|
Structure:
Search PDB for entries with ligand similarity: