Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM30891
Substrate
n/a
Meas. Tech.
Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation
IC50
3569.49±n/a nM
Citation
 PubChem, PC Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM30891
Synonyms:
MLS000049147 | N-(2-furanylmethyl)-7-hydroxy-2-oxo-1-benzopyran-3-carboxamide | N-(2-furfuryl)-7-hydroxy-2-keto-chromene-3-carboxamide | N-(2-furylmethyl)-7-hydroxy-2-oxo-2H-chromene-3-carboxamide | N-(furan-2-ylmethyl)-7-hydroxy-2-oxochromene-3-carboxamide | N-(furan-2-ylmethyl)-7-oxidanyl-2-oxidanylidene-chromene-3-carboxamide | SMR000074483 | cid_5398663
Type:
Small organic molecule
Emp. Form.:
C15H11NO5
Mol. Mass.:
285.2515
SMILES:
Oc1ccc2cc(C(=O)NCc3ccco3)c(=O)oc2c1
Structure:
Search PDB for entries with ligand similarity: