Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48923
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00544±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48923
Synonyms:
3-[[2-(3,5-dimethyl-1-pyrazolyl)-5-ethoxycarbonyl-4-pyrimidinyl]amino]benzoic acid | 3-[[2-(3,5-dimethylpyrazol-1-yl)-5-ethoxycarbonyl-pyrimidin-4-yl]amino]benzoic acid | 3-[[2-(3,5-dimethylpyrazol-1-yl)-5-ethoxycarbonylpyrimidin-4-yl]amino]benzoic acid | 3-[[5-carbethoxy-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]amino]benzoic acid | MLS000040650 | SMR000043152 | cid_662434
Type:
Small organic molecule
Emp. Form.:
C19H19N5O4
Mol. Mass.:
381.3853
SMILES:
CCOC(=O)c1cnc(nc1Nc1cccc(c1)C(O)=O)-n1nc(C)cc1C
Structure:
Search PDB for entries with ligand similarity: