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Target
D(1B) dopamine receptor
Ligand
BDBM48926
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00455±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48926
Synonyms:
2-ethyl-4-(1-piperidinyl)benzofuro[3,2-d]pyrimidine;hydrochloride | 2-ethyl-4-piperidin-1-yl-[1]benzofuro[3,2-d]pyrimidine;hydrochloride | 2-ethyl-4-piperidino-benzofuro[3,2-d]pyrimidine;hydrochloride | MLS000041578 | SMR000044212 | cid_6602805
Type:
Small organic molecule
Emp. Form.:
C17H19N3O
Mol. Mass.:
281.3523
SMILES:
CCc1nc(N2CCCCC2)c2oc3ccccc3c2n1
Structure:
Search PDB for entries with ligand similarity: