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Target
D(1B) dopamine receptor
Ligand
BDBM48944
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00712±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48944
Synonyms:
1'-{[4-(3-chlorophenyl)piperazin-1-yl]methyl}spiro[1,3-dioxane-2,3'-indol]-2'(1'H)-one | 1'-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-2'-spiro[1,3-dioxane-2,3'-indole]one | 1'-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]spiro[1,3-dioxane-2,3'-indole]-2'-one | 1'-[[4-(3-chlorophenyl)piperazino]methyl]spiro[1,3-dioxane-2,3'-indoline]-2'-one | MLS000046164 | SMR000031773 | cid_3239182
Type:
Small organic molecule
Emp. Form.:
C22H24ClN3O3
Mol. Mass.:
413.897
SMILES:
Clc1cccc(c1)N1CCN(CN2C(=O)C3(OCCCO3)c3ccccc23)CC1
Structure:
Search PDB for entries with ligand similarity: