Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM48978
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen
EC50
0.00105±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Counterscreen PubChem Bioassay (2007)[AID] 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Homo sapiens (Human)
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM48978
Synonyms:
2-(4-fluorophenyl)-5-[(phenylmethyl)amino]-1,3-oxazole-4-carbonitrile | 2-(4-fluorophenyl)-5-[(phenylmethyl)amino]-4-oxazolecarbonitrile | 5-(benzylamino)-2-(4-fluorophenyl)-1,3-oxazole-4-carbonitrile | 5-(benzylamino)-2-(4-fluorophenyl)oxazole-4-carbonitrile | MLS000100635 | SMR000018442 | cid_854894
Type:
Small organic molecule
Emp. Form.:
C17H12FN3O
Mol. Mass.:
293.2951
SMILES:
Fc1ccc(cc1)-c1nc(C#N)c(NCc2ccccc2)o1
Structure:
Search PDB for entries with ligand similarity: