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Target
D(1A) dopamine receptor
Ligand
BDBM34210
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.0236±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM34210
Synonyms:
3-(3-Chloro-4-morpholin-4-yl-2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-benzoic acid methyl ester | 3-(3-chloro-2,5-diketo-4-morpholino-3-pyrrolin-1-yl)benzoic acid methyl ester | 3-[3-chloro-4-(4-morpholinyl)-2,5-dioxo-1-pyrrolyl]benzoic acid methyl ester | MLS000034016 | SMR000014938 | cid_650622 | methyl 3-(3-chloro-4-morpholin-4-yl-2,5-dioxopyrrol-1-yl)benzoate | methyl 3-[3-chloranyl-4-morpholin-4-yl-2,5-bis(oxidanylidene)pyrrol-1-yl]benzoate
Type:
Small organic molecule
Emp. Form.:
C16H15ClN2O5
Mol. Mass.:
350.754
SMILES:
COC(=O)c1cccc(c1)N1C(=O)C(Cl)=C(N2CCOCC2)C1=O |t:15|
Structure:
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