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Target
D(1A) dopamine receptor
Ligand
BDBM49045
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.0188±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49045
Synonyms:
3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxylic acid ethyl ester | 3-methyl-5-morpholinosulfonyl-coumarilic acid ethyl ester | MLS000095958 | SMR000031506 | cid_3237275 | ethyl 3-methyl-5-(morpholin-4-ylsulfonyl)-1-benzofuran-2-carboxylate | ethyl 3-methyl-5-morpholin-4-ylsulfonyl-1-benzofuran-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H19NO6S
Mol. Mass.:
353.39
SMILES:
CCOC(=O)c1oc2ccc(cc2c1C)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: