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Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM51322
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM51322
Synonyms:
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[3-(3-methoxyphenyl)-2-isoxazolin-5-yl]methanone | 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[3-(3-methoxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanone | 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[3-(3-methoxyphenyl)-4,5-dihydroisoxazol-5-yl]methanone | 8-{[3-(3-methoxyphenyl)-4,5-dihydroisoxazol-5-yl]carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane | MLS000092686 | SMR000028377 | cid_3244043
Type:
Small organic molecule
Emp. Form.:
C18H22N2O5
Mol. Mass.:
346.3777
SMILES:
COc1cccc(c1)C1=NOC(C1)C(=O)N1CCC2(CC1)OCCO2 |t:9|
Structure:
Search PDB for entries with ligand similarity: