Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM51364
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM51364
Synonyms:
(4-thiophen-2-yl-2-pyrimidinyl)thiourea | (4-thiophen-2-ylpyrimidin-2-yl)thiourea | 1-(4-thiophen-2-ylpyrimidin-2-yl)thiourea | MLS000763979 | N-[4-(2-thienyl)-2-pyrimidinyl]thiourea | SMR000336116 | [4-(2-thienyl)pyrimidin-2-yl]thiourea | cid_1482759
Type:
Small organic molecule
Emp. Form.:
C9H8N4S2
Mol. Mass.:
236.317
SMILES:
NC(=S)Nc1nccc(n1)-c1cccs1
Structure:
Search PDB for entries with ligand similarity: