Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM41669
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
591±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM41669
Synonyms:
4-[3-(4-chlorophenyl)-2-pyrazolin-1-yl]-N-[3-(dimethylamino)propyl]benzenesulfonamide | 4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-N-[3-(dimethylamino)propyl]benzenesulfonamide | 4-[5-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]-N-[3-(dimethylamino)propyl]benzenesulfonamide | MLS000530254 | SMR000135230 | cid_2837694
Type:
Small organic molecule
Emp. Form.:
C20H25ClN4O2S
Mol. Mass.:
420.956
SMILES:
CN(C)CCCNS(=O)(=O)c1ccc(cc1)N1CCC(=N1)c1ccc(Cl)cc1 |c:20|
Structure:
Search PDB for entries with ligand similarity: