Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM51674
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
563±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM51674
Synonyms:
4-Butyl-6-chloro-8-diethylaminomethyl-7-hydroxy-chromen-2-one | 4-butyl-6-chloranyl-8-(diethylaminomethyl)-7-oxidanyl-chromen-2-one | 4-butyl-6-chloro-8-(diethylaminomethyl)-7-hydroxy-1-benzopyran-2-one | 4-butyl-6-chloro-8-(diethylaminomethyl)-7-hydroxy-coumarin | 4-butyl-6-chloro-8-(diethylaminomethyl)-7-hydroxychromen-2-one | MLS000551591 | SMR000145516 | cid_5541651
Type:
Small organic molecule
Emp. Form.:
C18H24ClNO3
Mol. Mass.:
337.841
SMILES:
CCCCc1cc(=O)oc2c(CN(CC)CC)c(O)c(Cl)cc12
Structure:
Search PDB for entries with ligand similarity: