Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47767
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47767
Synonyms:
3-(phenoxymethyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-3-(phenoxymethyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-5-(phenoxymethyl)-4H-1,2,4-triazole-3-thiol | MLS000676944 | SMR000271129 | cid_702854
Type:
Small organic molecule
Emp. Form.:
C16H15N3OS
Mol. Mass.:
297.375
SMILES:
S=c1[nH]nc(COc2ccccc2)n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: