Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47781
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47781
Synonyms:
5-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]-5-oxopentanoic acid | 5-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]-5-oxopentanoic acid | 5-[4-[hydroxy(diphenyl)methyl]piperidino]-5-keto-valeric acid | 5-[4-[oxidanyl(diphenyl)methyl]piperidin-1-yl]-5-oxidanylidene-pentanoic acid | MLS000715040 | SMR000275019 | cid_1074070
Type:
Small organic molecule
Emp. Form.:
C23H27NO4
Mol. Mass.:
381.4648
SMILES:
OC(=O)CCCC(=O)N1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: