Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM47784
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
EC50
30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM47784
Synonyms:
2-[[(2-acetamido-5-bromo-phenyl)-phenyl-methyl]amino]acetic acid methyl ester | 2-[[(2-acetamido-5-bromophenyl)-phenylmethyl]amino]acetic acid methyl ester | MLS000692775 | SMR000285200 | cid_2870391 | methyl 2-[[(2-acetamido-5-bromanyl-phenyl)-phenyl-methyl]amino]ethanoate | methyl 2-[[(2-acetamido-5-bromophenyl)-phenylmethyl]amino]acetate
Type:
Small organic molecule
Emp. Form.:
C18H19BrN2O3
Mol. Mass.:
391.259
SMILES:
COC(=O)CNC(c1ccccc1)c1cc(Br)ccc1NC(C)=O
Structure:
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